منابع مشابه
Intelligent platelet inhibitors are on the horizon.
Hemostasis is a tightly regulated physiological sequence of events that maintains vascular integrity and imminent blood loss after vessel injury. Platelets play a critical role in primary hemostasis and in regulation of coagulation. Under physiological conditions, hemostasis and thrombosis are in a fragile equilibrium. Uncontrolled platelet activation leads to intravascular thrombosis and organ...
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1079 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
متن کاملNew Drugs on the Horizon: Matrix Metalloproteinase Inhibitors.
Matrix metalloproteinases (MMPs) are a family of enzymes involved in a number of normal cellular processes, such as regulation of endometrial growth and menstruation, and abnormal processes, such as tumor growth, invasion, and metastasis. There are now 18 distinct enzymes that fall into three functional classifications based on their substrate target: collagenases which degrade fibrillar collag...
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Today, viral marketing with benefits such as lower cost and greater effectiveness, has become an ideal option for advertising strategy. This study was conducted with the aim of presenting a viral recovery model in the elections of the Islamic Consultative Assembly in the tenth and eleventh terms of Iran. Required data were collected using a questionnaire. The statistical population in this stud...
متن کاملModeling Viral Capsid Assembly.
I present a review of the theoretical and computational methodologies that have been used to model the assembly of viral capsids. I discuss the capabilities and limitations of approaches ranging from equilibrium continuum theories to molecular dynamics simulations, and I give an overview of some of the important conclusions about virus assembly that have resulted from these modeling efforts. To...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2005
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd1834